EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 14-Dec-2025 04:11 ET (14-Dec-2025 09:11 GMT/UTC)

City of Hope appoints leading lung cancer expert Dr. Christine M. Lovly to head national thoracic oncology program

City of Hope
Business Announcement

City of Hope today announced that internationally recognized physician-scientist Christine M. Lovly, M.D., Ph.D., F.A.S.C.O., will spearhead the development of its new national thoracic oncology program, furthering City of Hope’s mission to deliver exceptional multidisciplinary care and transformative research for patients with lung cancer. Dr. Lovly’s appointment is effective Jan. 1.

Supervised exercise improves strength and physical performance in patients with advanced breast cancer

Associação Advanced Breast Cancer Global Alliance
Reports and Proceedings

Aerobic and resistance exercise can significantly improve physical performance in patients living with metastatic breast cancer according to new results presented at the Advanced Breast Cancer Eighth International Consensus Conference (ABC8) on Friday. Until now, there has been limited evidence that physical exercise can improve muscle mass and strength in patients with metastatic cancer, partly because they were often excluded from studies.

Funder: EU Horizon 2020 research and innovation programme, National Health and Medical Research Council of the Australian Government
Meeting: Advanced Breast Cancer Eighth International Consensus Conference (ABC 8)

Distinguished cancer researcher Stuart S. Martin, PhD, named Chair of the Department of Pharmacology & Physiology at UM School of Medicine

University of Maryland School of Medicine
Business Announcement

Stuart S. Martin, PhD, an internationally recognized breast cancer researcher, has been appointed Chair of the University of Maryland School of Medicine (UMSOM) Department of Pharmacology & Physiology, Dean Mark T. Gladwin, MD, announced today. As the distinguished Drs. Angela and Harry Brodie Professor of Translational Cancer Research, Dr. Martin has served as Interim Chair of the Department over the past year. He also serves as the Deputy Director of the University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC), one of 57 National Cancer Institute (NCI)-designated comprehensive cancer centers in the nation.

Discovery reveals ‘handbrake’ that controls cancer drug response

University of Oxford
Peer-Reviewed Publication

Oxford University and Austrian researchers uncover a previously unknown ‘handbrake’ mechanism controlling how cells respond to cancer drugs, reshaping global understanding of cell metabolism and drug resistance.

Journal: Science

The enzyme that doesn’t act like one

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Peer-Reviewed Publication

A surprising discovery reveals how a single protein helps cells decide when to make the building blocks of DNA. Researchers at CeMM, together with collaborators from the University of Oxford, have discovered that the enzyme NUDT5 acts not through its chemical activity, but as a physical “scaffold” that helps switch off a key metabolic pathway when purine levels are high. The study, published in Science (DOI 10.1126/science.adv4257), reveals a mechanism with implications for cancer treatment and inherited metabolic disorders.

Journal: Science

Moffitt study reveals way to spark immune hotspots that attack tumors

H. Lee Moffitt Cancer Center & Research Institute
Peer-Reviewed Publication

Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary lymphoid-like structures, or TLSs. These immune cell clusters are increasingly linked to improved outcomes and treatment responses in cancer. Results of their study was published in the Proceedings of the National Academy of Sciences.

Journal: Proceedings of the National Academy of Sciences
Funder: NIH/National Cancer Institute, CJG Fund, Chris Sullivan Fund, V Foundation, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, Melanoma Research Foundation

Inflammation may be responsible for driving earliest stages of lung cancer

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

Spatial maps of lung precancer and cancer cells at different points in development advance understanding of the earliest stages of lung cancer

Findings highlight inflammation as a driver of lung tumor initiation

Targeting inflammation could be a potential therapeutic strategy to intercept lung cancer and improve patient outcomes

Journal: Cancer Cell

Informal human milk sharing among US mothers

JAMA Network
Peer-Reviewed Publication

About The Study: In this large, diverse sample of first-time mothers in the U.S., 1 in 27 participants reported feeding their infants shared human milk. Prior work indicates that families engage in many, but not all, recommended milk sharing risk mitigation measures and fear disclosing their milk sharing to practitioners. Given the prevalence in this study, pediatric practitioners should be aware that milk sharing occurs across demographics; they can counsel families considering or using shared milk on risks and risk-reduction strategies recommended by the Academy of Breastfeeding Medicine and the American Academy of Nursing, while noting that evidence on home pasteurization is still evolving.

Journal: JAMA Network Open

New high-efficiency gene editing method enhances speed and reduces costs in biomedical research

Impact Journals LLC
Peer-Reviewed Publication

BUFFALO, NY — November 6, 2025 — A new research paper was published in Volume 16 of Genes & Cancer on October 31, 2025, titled “P3a site-specific and cassette mutagenesis for seamless protein, RNA and plasmid engineering.”

Journal: Genes & Cancer

Relapses of breast cancer: Discovery of a key cellular resistance mechanism

CNRS
Peer-Reviewed Publication

A cellular resistance mechanism at the origin of relapses of triple-negative breast cancer has recently been discovered by scientists from CNRS, Institut Curie and Université Paris Cité. Their findings have been published in Cancer Research, a journal of the American Association for Cancer Research, on 6 November 2025.

Journal: Cancer Research

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