Sounding the alarm: new survey shows men are unaware of ‘young man’s disease’
Reports and Proceedings
Updates every hour. Last Updated: 30-Jun-2025 07:10 ET (30-Jun-2025 11:10 GMT/UTC)
Men at the greatest risk of testicular cancer might not even know it. While it's considered a ‘young man’s disease,’ a survey commissioned by The Ohio State University Comprehensive Cancer Center finds nearly 90% of Americans don’t realize that testicular cancer is most common in men under the age of 40.
Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University observe and model how the enzyme ADAR1 interacts with double-stranded RNA, which may be useful for future cancer treatment strategies.
Scientists from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, have developed a novel ultrasound-driven therapy that activates dormant cancer drugs directly inside tumors. By combining low-intensity ultrasound with specially designed nanoparticles, the team achieved a 99% tumor suppression rate and 66.7% cure rate in mice. This non-invasive approach minimizes side effects and could revolutionize targeted cancer treatment.
A new study from the University of Rochester reveals that key optical measurements of tumor collagen structure differ between Black and White patients with breast and colon cancer. Using second-harmonic generation imaging, researchers analyzed collagen organization in over 300 tumor samples and found significant racial differences in a prognostic marker known as the forward-to-backward scattering ratio (F/B), which is linked to metastatic risk. These findings highlight the need for racially diverse clinical trials to ensure that emerging diagnostic tools accurately predict cancer outcomes for all patient populations.
For both men and women without a Bachelor’s degree (BA), a new study in JAMA Health Forum found that mortality between 2011-2023 was markedly higher than would have been expected had death rates from 2006-2010 continued. Among 564,855 excess deaths in 2023 alone, 481,211 occurred among people without a BA—a 26 percent increase in mortality among this population, compared to pre-2010 trends. In contrast, mortality only increased by eight percent among people who received a BA.
Marcela Maus, MD, PhD, director of the Cellular Immunotherapy Program and the Paula J. O'Keeffe Endowed Chair of the Mass General Cancer Center, is senior author and Stefanie Bailey, PhD, Hana Takei, and Giulia Escobar, PhD of the Krantz Family Center for Cancer Research at Massachusetts General Hospital are co-lead authors of a paper published in Science Translational Medicine, “IFN-g-resistant CD28 CAR-T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models.”
(WASHINGTON, June 13, 2025) – Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more likely to develop breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a rare T-cell lymphoma, compared with similar women without these genetic mutations, according to a study published today in Blood Advances.
In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets. Researchers at the Technical University of Munich (TUM) have developed a method for tracking these cells in the body. This new approach could deepen our understanding of cellular therapies and help make future treatments safer.