Newly identified prostate cell type may help explain why enlarged prostate develops in one region of gland
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Updates every hour. Last Updated: 20-Oct-2026 10:16 ET (20-Oct-2026 14:16 GMT/UTC)
This study shows that early gastric cancer arises within an inflammation-associated spatial niche and identifies the SOX9-CXCL axis as a targetable mechanism.
A cancer drug currently being tested in patients may have entered clinical trials based on an incorrect understanding of how it works, according to a new study led by the University of Sydney in collaboration with Goethe University, Oxford University and the Institute of Cancer Research, London.
Results from ECOG-ACRIN’s CompassHER2-pCR trial identify clinical and molecular predictors of pathologic complete response (pCR) after 12 weeks of THP, a less intensive neoadjuvant regimen combining one chemotherapy drug with two HER2-targeted drugs. It is the largest prospective trial of this approach in stage II-IIIA HER2+ breast cancer. Follow-up is ongoing to assess 3-year recurrence-free survival among patients who had a pCR. Published in JCO, the findings will be featured in a podcast.