Nanomedicines often acquire a protein corona in the bloodstream before reaching the brain. A new Perspective in Science Bulletin argues that this evolving layer should be engineered as a programmable interface that can guide recognition, transcytosis and release across the blood-brain barrier.

Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples. A cross-disciplinary research team at The Hong Kong University of Science and Technology (HKUST) has developed a novel generative AI (GenAI) framework that can produce high-fidelity virtually stained images even when training image pairs are imperfectly aligned, paving the way for faster and more tissue-saving histopathology workflows. The study titled “Generative AI for misalignment-resistant virtual staining to accelerate histopathology workflows” was recently published in the international journal Nature Communications. 

Researchers invent a laser technique that reveals the hidden forces shaping proteins, advancing a future of precision medicine engineered with quantum precision.

A chemotherapy drug and a gene-silencing molecule exploit an “eat me” signal on dying cancer cells to stop tumor growth.

Researchers combined adaptive optics and parallel optical coherence tomography to capture high-speed, 3D views of individual cells in the living retina. This non-invasive advance could drastically improve the early  detection and monitoring of chorioretinal diseases.