2-Dec-2025
Unraveling the fungi-cancer connection
ResearchPeer-Reviewed Publication
A growing body of evidence indicates that the microbiome within the gut and tumors significantly influences cancer initiation, progression, and treatment response. Current research primarily focuses on bacteria, whilst the role of fungi is only now gaining attention. The authors address key questions that have caused confusion and hindered clinical translation: (a) Why should we value the role of mycobiome in oncological research? (b) What will the relationship between fungi and bacteria be in cancer progression? (c) How will the fungi impact cancer? (d) Can we target fungi for development of intervention strategies in anticancer treatment? (e) Will the effort and investment pay back in mycobiome-driven cancer research?
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- Research
- Funder
- Top Talent Support Program for Young and Middle aged People of Wuxi Health Commission, General Program of Wuxi Medical Center of Nanjing Medical University, Quality Talent Program of Wuxi Medical Center of Nanjing Medical University, National Natural Science Foundation of China, MOST Key R&D Program of China, Program of Shanghai Academic/Technology Research Leader