Oral nanomaterial formulations enhance drug stability, solubility, mucosal penetration and targeted delivery for gastrointestinal therapy. This review compares metallic and non-metallic nanomaterials and highlights the strong clinical translation potential of non-metallic systems, especially selenium nanoparticles (SeNPs).

Researchers have developed a novel ratiometric SERS platform utilizing dual functionalized bioprobes (TiO₂-CV-rBSA-FA and IO-AR-PDA-EpCAM), addressing the critical challenge of signal instability in SERS-based detection of rare circulating tumor cells (CTCs). This platform establishes a stable and reliable approach for sensitive CTC detection.

In short, we report an inverse phase enhancement (IPE) strategy to fabricate high-performance graphene paper (IPE-GP) exhibiting high strength (63.3 MPa) and high thermal conductivity (1325 W/m·K) at a minimal polymer loading of 5.9%. Using this conspicuous IPE-GP, we fabricated graphene composites that attained a record in-plane thermal conductivity of 802 W/m·K of polymer bulk composites.

Researchers have developed an artificial intelligence model that learns from real match data to evaluate and improve football attacking strategies against compact "low block" defenses. By modeling both on-ball decisions and off-ball movements, the model generates more coordinated and creative attacking solutions, offering practical decision support for coaches and analysts.

Adequate boron (B) supply is essential for optimal growth and yield formation in rapeseed (Brassica napus L.). With boron-deficient soils affecting croplands worldwide, developing varieties with enhanced boron-use efficiency represents a sustainable strategy to safeguard productivity. Central to this effort is the identification of genes that regulate boron homeostasis. 

A recent study has constructed a disaster picture of the "April 27" tornado that struck Guangzhou, China in 2024 by integrating Unmanned Aerial Vehicle (UAV) imagery, detailed ground-based post-disaster surveys, and high-precision meteorological simulations. The research analyzed the tornado's trajectory, intensity, and its impact on building structures, providing a reference for tornado disaster assessment and the wind-resistant design of engineering structures in South China.

High concentrations of free fatty acid (FFA) in ketotic dairy cows activate endoplasmic reticulum (ER) stress pathways, contributing to mammary epithelial cell apoptosis and reduced milk yield. The study sets the stage for in vivo trials to validate ER stress inhibitors like Tauroursodeoxycholate (TUDCA) as practical solutions for managing ketosis and enhancing dairy cows health.

Researchers have established a comprehensive public dataset, GlycoHBF, which provides a detailed map of proteins and their glycosylation (N-glycosylation) across 15 types of human body fluids. Using standardized processing and advanced mass spectrometry, the study reveals significant molecular heterogeneity among fluids like plasma, urine, saliva, tears, and cerebrospinal fluid. This work provides a rigorous analytical framework and a baseline reference that will accelerate the discovery of liquid biopsy biomarkers for diseases including cancer and neurological disorders.