A collaborative research team led by scientists from the China National Center for Bioinformation, a research center affiliated with the Chinese Academy of Sciences (CAS), together with the CAS Institute of Zoology and Quzhou Affiliated Hospital of Wenzhou Medical University, has constructed a high-precision Human Immune Aging Clock (HIAC). The work systematically characterizes the multiscale dynamics of immunosenescence and identifies the transcription factor RUNX1 as a functional "brake" on T-cell senescence.