About The Study: Findings from this systematic review indicated that nonregistration, premature discontinuation due to poor recruitment, and nonpublication of randomized clinical trial (RCT) results remained major challenges, especially for non–industry-sponsored trials. To mitigate these challenges, requirements enforced by funders and ethics committees also taking into account legal obligations should be considered and empirically evaluated.
Corresponding Author: To contact the corresponding author, Matthias Briel, MD, PhD, email matthias.briel@usb.ch.
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Editor’s Note: Please see article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Media advisory: This study is being presented at the 10th International Congress on Peer Review and Biomedical Publication. For more information on the Congress, go to peerreviewcongress.org.
Journal
JAMA Network Open