About The Study: In this cohort study of middle-aged and older adults across 4 countries, both higher maternal and paternal education were generally associated with slower cognitive decline, and these associations were mediated by participants’ own education. These findings highlight the long-term relevance of parental education for offspring cognitive health across diverse cultural or socioeconomic contexts, and support the potential benefits of improving educational attainment to reduce intergenerational disparities in late-life cognitive health.
Corresponding Author: To contact the corresponding author, Vivian Yawei Guo, PhD, email guoyw23@mail.sysu.edu.cn.
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(doi:10.1001/jamanetworkopen.2025.13036)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.
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