University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center (UMGCCC) researchers, who are on faculty at the University of Maryland School of Medicine, presented findings at the American Association for Cancer Research (AACR) Annual Meeting in Chicago last month.
These included a study conducted with researchers at the National Cancer Institute, which evaluated lifetime alcohol consumption and found that current drinkers who drank an average of 14 or more drinks per week throughout adulthood compared to current drinkers who drank less than one drink per week throughout adulthood had a 25 percent higher risk of colorectal cancer, particularly for rectal cancer.
Others tested the safety of a novel immunotherapy treatment in patients with relapsed or refractory acute myeloid leukemia in an early-stage clinical trial. Researchers also presented data that may guide the optimization of CAR T-cell therapy in myeloma patients, leading to greater success and fewer side effects of this promising immunotherapy.
UMGCCC #AACR25 Photo Gallery
AACR25 Highlights
Association of increasing alcohol intake over the lifetime with colorectal adenoma and colorectal cancer risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial
Caitlin P. O'Connell, Sonja I. Bernd1, Kenechukwu Chudy-Onwugaje, Andrew T. Kunzmann, Wen-Yi Huang, Kathryn Hughes Barry, Erikka Loftfield
Intravenous infusion of the allosteric small molecule STING agonist CRD3874-SI in patients with relapsed or refractory acute myeloid leukemia: A Phase I trial
Maria R. Baer, Vu H. Duong, Oyinkansola Arasanmi, Devon T. Issac, Sunita Philip, Megan Wagner, Ar'Lena Hassan, Feyruz V. Rassool, Sandip Middya, Ritesh Shrivastava, Anindita Middya, Nagaswamy Mane, Thanilsana Soram, Kavita Puniya, Nidhi Rawat, Debjani Chakraborty, Rubeena R. Mansuri, Anul Singh, Rajib Ghosh, Anuj Gautam, Sourav Basu, Monali Banerjee, Arjun Surya
Distinct expansion, phenotype, function, and toxicity of cilta-cel vs. ide-cel CAR T cells in the real world
Djordje Atanackovic, Tim Luetkens, Dina Schneider, Peirong Hu, Xu Wang, Amol C. Shetty, Luke Tallon, Imari Patel, Rohan Singh, Etse Gebru, Rediet Mulatu, Destiny Omili, Daniel Yamoah, Xiaoxuan Fan, Aerielle Matsangos, Patricia Lesho, Kenneth A. Dietze, Ariel A. Fromowitz, Kim Hankey, Saurabh Dahiya, Jean A. Yared, Nancy M. Hardy, Rima Koka, Michael E. Kallen, Ashraf Badros, Aaron P. Rapoport, Mehmet Kocoglu