image: Join us and Dr. Yong in Berlin this October to know more about the Stem Cell Educator (SCE) therapy, which addresses mitochondrial dysfunctions through immune modulation and tissue regeneration.
Credit: World Mitochondria Society (WMS)
The World Mitochondria Society (WMS) is preparing for its annual Targeting Mitochondria 2024 conference, which will focus on innovative strategies to “charge” cells by supplying them with extra mitochondria to enhance cellular function and combat diseases.
The Scientific Board of WMS has emphasized the urgent need to discover the most effective methods for delivering mitochondria to cells, potentially transforming treatments for a variety of conditions driven by mitochondrial dysfunction.
"The challenge we face is finding efficient methods to provide cells with healthy mitochondria, enabling them to produce energy more effectively and regulate vital signaling pathways," stated Volkmar Weissig (Midwestern University, USA) and Marvin Edeas (Université Paris Cité, France), from the Scientific Board of WMS. "This strategy holds immense promise for revolutionizing therapies aimed at addressing mitochondrial dysfunctions, which are implicated in autoimmune diseases, neurodegenerative disorders, cancer, infections, and aging-related conditions."
The upcoming conference will feature world-leading experts who will discuss advancements in mitochondrial transfer, focusing on the most promising techniques for enhancing cellular energy and supporting regeneration in damaged tissues and organs.
Dr. Yong Zhao: Transformative Approaches to Mitochondrial Dysfunction
A highlight of the last session will be the presentation by Dr. Yong Zhao from Throne Biotechnologies, USA, who has developed the groundbreaking Stem Cell Educator (SCE) therapy, a cutting-edge approach that addresses mitochondrial dysfunctions through immune modulation and tissue regeneration.
Dr. Zhao’s work focuses on the correction of autoimmune diseases and mitochondrial disorders, with a proven track record in treating patients with Type 1 Diabetes (T1D) and Alopecia Areata (AA). His presentation will detail how SCE therapy corrects mitochondrial dysfunction at both the local and systemic levels by using cord-blood-derived multipotent stem cells (CB-SC) to “educate” immune cells, ultimately leading to restored immune tolerance and improved tissue health. Clinical trials have shown that SCE therapy not only restores beta-cell function in T1D patients but also promotes long-term hair regrowth in AA sufferers.
This innovative approach highlights how mitochondrial transfer, coupled with immune education, can revolutionize treatment for autoimmune and inflammatory diseases.
Mitochondrial Medicine 2024: Session Highlights
The last session of Targeting Mitochondria 2024, “Mitochondrial Medicine 2024: From Bench to Bedside”, will also feature presentations from other leading experts in the field, including:
- Jonathan R. Brestoff, Washington University in St. Louis School of Medicine, USA, discussing the potential of mitochondria transfer.
- Mark Kindy, James A. Haley VA Hospital and University of South Florida, USA, presenting on mitochondrial transplantation and its role in improving cellular energy metabolism.
- Ana Andreazza, University of Toronto, Canada, exploring the intersection of mitochondrial function and psychiatric disorders, focusing on biomarkers and patient stratification.
- Jignesh D. Pandya, Walter Reed Army Institute of Research, USA, addressing mitochondria-specific targets and therapeutic strategies following traumatic brain injury.
- Elena Palma, King’s College London, United Kingdom, discussing diagnostic and therapeutic interventions in human liver disease by targeting giant mitochondria (megamitochondria).
Advancing Mitochondrial Transfer to Combat Diseases
The World Mitochondria Society is dedicated to advancing scientific knowledge and therapeutic applications related to mitochondrial function. Through its annual meetings, the WMS continues to explore cutting-edge treatments that utilize the potential of mitochondrial transfer, aiming to combat diseases driven by mitochondrial dysfunction. The society aims to foster collaboration on the latest therapeutic approaches, including the potential of transferring healthy mitochondria to organs and tissues to restore cellular energy and modulate vital signaling pathways.
For more information on Targeting Mitochondria 2024, or to register for the conference, please visit www.wms-site.com.
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