Multimedia Release 18-Apr-2024

Moffitt researchers discover new therapeutic target for non-small cell lung cancer

Disrupting Jagged2 signaling reprograms immune cells to fight tumors

Peer-Reviewed Publication

H. Lee Moffitt Cancer Center & Research Institute

**image:**
**Paulo Rodriguez, Ph.D., Chair of the Department of Immunology at Moffitt Cancer Center**
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Credit: Moffitt Cancer Center

Journal

Immunity

DOI

10.1016/j.immuni.2024.03.020

Method of Research

Experimental study

Subject of Research

Cells

Article Title

Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

Article Publication Date

17-Apr-2024

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