Synthetic Circuits (IMAGE)
Caption
Circuit-host interactions and their consequences across scales. Synthetic circuits and the host form a dynamic, multilayered relationship involving both generic and system-specific interactions, hence mutually regulating the behaviours of each other. As the circuit-host coupling alters cellular growth, the influences of coupling can propagate across scales, impacting single-cell dynamics, population behaviors and the emergence of spatial ecology. Here, red and green cells represent two distinct phenotypes caused by circuit-host interactions; green and red patches are cell clusters formed by the two phenotypes.
Credit
<i>Nature Microbiology</i> ISSN 2058-5276 (online)
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