Thick Skin and Thin Skin (IMAGE)
Caption
At top, the epidermis of a wild-type mouse is thick, and its granular layer is prominent. At bottom, the epidermis of a Satb1 knockout mouse is significantly thinner, and its granular layer is diminished. Satb1 controls the expression of many genes responsible for epidermal architecture.
Credit
University of Bradford, Lawrence Berkeley National Laboratory
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