Immunosignature Profiling (IMAGE)

Arizona State University

Immunosignature Profiling

Caption

In immunosignaturing, a chemical marker causes the antigen-antibody pair to fluoresce, with the magnitude of fluorescence indicating the strength of antigen-antibody binding (red is strong binding, blue is weak). A single drop of blood, containing an individual's complete set of antibodies, is spread across an array of 10,000 random sequence peptides, imprinted on a microarray slide, revealing the immune system's complete pattern of activity after exposure to a pathogen, a vaccine or any other factor provoking a change in the antibody portrait.

Credit

The Biodesign Institute at Arizona State University

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