Mechanism for Sensing Magnesium Ions Resulting from Ribosome Destabilization (IMAGE)

_Tokyo Institute of Technology

Mechanism for Sensing Magnesium Ions Resulting from Ribosome Destabilization

Caption

The gene, mgtL, controlling the expression of the membrane protein MgtA which transports magnesium into cells has a ribosome-destabilizing sequence, and translation is aborted when the magnesium concentration inside the cell is low. There is a mechanism which turns on MgtA synthesis when mgtL translation is aborted, and it is thought that the resulting abundant expression of MgtA raises the magnesium ion concentration inside the cell.

Credit

Hideki Taguchi

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