KAIST Develops “24/7 Unmanned Synthesis Platform” Using Robots and Light to Produce Drug Candidates (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

KAIST Develops “24/7 Unmanned Synthesis Platform” Using Robots and Light to Produce Drug Candidates

Caption

Figure 1. The research team developed a single-atom editing method that replaces the oxygen atom of furan with nitrogen, directly converting furans into N-methyl pyrroles, a key scaffold in drug development. The team implemented this method in a continuous-flow process driven by visible light, which allows the synthesis to be automated. (a) Design of new tailored photocatalysts. (b, c) Construction and overall view of the automated continuous-flow photoreaction platform. (d) Expansion of the N-methyl pyrrole library using natural-product-based compounds. Courtesy of KAIST

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KAIST

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