Schematic representation of stage II of trans-splicing via Spliced Leader (SL) RNA. (IMAGE)

University of Liège

Schematic representation of stage II of trans-splicing via Spliced Leader (SL) RNA.

Caption

Prior to the reaction (trans-C* complex, left), the SL exon (purple) and the 5′ untranslated region of the pre-mRNA (5’UTR, pink) are positioned within the trans-spliceosome. During stage II, the SL exon is attached to the pre-mRNA to form the mature messenger RNA carrying the SL (trans-P complex, on the right), whilst the remaining RNA sequences are released in the form of a Y-shaped branched structure. The branching point is indicated in red. IGS: intergenic sequence.

Credit

Théo Nadenoen

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