Fig. 2. Synergistic Actions of Polyherbal Formulations in Skin Anti-Aging (IMAGE)
Caption
Fig. 2. Synergistic Actions of Polyherbal Formulations in Skin Anti-Aging, A study conducted by Damle and Mallya (2015) examined the potential for synergistic anti-aging effects of a polyherbal preparation that included extracts from Glycyrrhiza glabra (liquorice) and Citrus aurantium (orange peel). Because of their high total phenolic content (TPC) and total flavonoid content (TFC), their study revealed that both extracts alone have strong antioxidant activity. Interestingly, the formulation showed the maximum TPC (530.00 ± 1.56 mg GAE/g), TFC (246.25 ± 1.03 mg RUE/g), and increased radical scavenging activity (DPPH 87.99 ± 0.64 %; H₂O₂ 72.47 ± 0.86 %) when mixed in a 1:2 ratio (orange peel: liquorice), confirming synergistic enhancement. A phytophospholipid complex containing the optimal combination greatly enhanced the preservation of polyphenols in the skin and maintained their antioxidant activity. The created cream also showed strong anti-elastase activity (28.02 ± 0.95 % at 3000 μg/ml), demonstrating the formulation's ability to fight skin aging. According to the authors, this polyherbal phospholipid complex provides a strong anti-aging cosmeceutical system that is stable and non-irritating.92.
Credit
Gulshan Rathore, et al
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