Fig. 3 (IMAGE)

The University of Osaka

Fig. 3

Caption

 The model showing transcriptional PBR cycles accumulate R-loops, which are converted into ADR-loops by Rad52, resulting in gross chromosomal rearrangements.

Credit

2026, Ran Xu et al., Transcriptional PBR cycles at pericentromeric repeats cause gross　chromosomal　rearrangements through Rad52-dependent ADR-loop formation, Nucleic Acids Research

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