Figure 2 | 3D-RSOM imaging of skin microvasculature hyperemia during PORH. (IMAGE)

Light Publishing Center, Changchun Institute of Optics, Fine Mechanics And Physics, CAS

Figure 2 | 3D-RSOM imaging of skin microvasculature hyperemia during PORH.

Caption

Figure 2 | 3D-RSOM imaging of skin microvasculature hyperemia during PORH. The skin vasculature at the forearm (4×2 mm2) of a healthy volunteer was measured by 3D-RSOM at every minute during the 10 min PORH test. (a-f) Cross-sectional images of 3D-RSOM volumes were acquired at six-time points with corresponding MIP images of the dermis layer in the coronal direction below each cross-sectional image. The white arrows in (e) indicate vessels that were visualized for the first time during the reactive hyperemia process. (g) The diameter changes of three vessels (white arrows 1, 2, and 3 in a) are characterized as the FWHM (full width at half maximum) values during the PORH test. (h) Changes in the total blood volume in the subpapillary dermis (SD) layer, the reticular dermis (RD) layer, and the whole dermis vasculature (DV) were computed from the 10 RSOM images obtained during the PORH test. (i) LDF&WLS measurements, including the blood flow, oxygen saturation (SO2), and partial blood volume (rHb) during the PORH test. Scale bar: 500 µm.

Credit

Vasilis Ntziachristos et al.

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CC BY

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