Illustration of IHoM and IHeM Models and Treatment Responses (IMAGE)

Higher Education Press

Illustration of IHoM and IHeM Models and Treatment Responses

Caption

(a) Schematic of IHoM and IHeM models. NC: neutral cells; AC: cells carrying antigen mutations; IC: immune-recognizable cells; EC: immune-escaped cells. (b) Response of IHoM and IHeM to monotherapies with chemotherapy or immune checkpoint blockade. (c) Changes in Shannon diversity of antigen mutations in IHeM before and after chemotherapy and responses under combination therapy.

Credit

Chen S, Hu Z, Zhou D

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