Possible mechanism of PDE4DIP causing LVNC through Rho-ROCK pathway. (IMAGE)

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Possible mechanism of PDE4DIP causing LVNC through Rho-ROCK pathway.

Caption

(A) PDE4DIP is located in the Golgi apparatus and regulates a series of physiological activities of cells through the Rho-ROCK pathway. (B) Simplified mechanism of PDE4DIP possibly causing LVNC.

Credit

Wuxia Gu, Hongyan Li, Wenjing Yuan, Xiaoqiong Fu, Rui Wang, Xiaohui Xu, Xuemei Liao, LingJuan Liu, Bo Pan, Jie Tian, Haixin Yuan, Yi Huang, Tiewei Lu

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License

CC BY-NC-ND

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