Comparison of synaptic strength during sleep and wakefulness (Firing rate in wakefulness > Firing rate in sleep) (IMAGE)
Caption
Temporal changes in synaptic connections during sleep and during wakefulness, and compared their mean values under conditions where the average firing rate during wakefulness (in the 11-neuron network shown in Figure 1) exceeds that of sleep. According to both the Hebbian and STDP rule, synaptic connections become more enhanced during wakefulness than during sleep (consistent with “SHY”) when there is a large difference in firing rate between wakefulness and sleep. On the other hand, when the difference in firing rate is small, synaptic connections become more enhanced during sleep than during wakefulness (consistent with “WISE”).
Credit
Fukuaki Kinoshita / Systems Pharmacology, University of Tokyo
Usage Restrictions
Credit must be given to the creator
License
Original content