The antiviral efficacy of MH3 Λ against MPXV. (IMAGE)
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(A) Representative plaques were mapped after treatment with varying concentrations of MH3 Λ. (B) Quantitative representation of plaque forming units is depicted. The percentage of plaque formation in the presence of varying concentrations of MH3 Λ inhibitor is expressed relative to the number of plaques observed without the inhibitor. (C) The antiviral efficacy of MH3 Λ was assessed via qPCR. (D) Effect of MH3 Λ on the mRNA expression levels of IL-6, IL-10, TNF-α, IL-1β, IL-12 and IFN-α in Vero cells infected with MPXV.
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