Figure 4: Methods of inducing muscle atrophy in cell models (IMAGE)

Sichuan International Medical Exchange and Promotion Association

Figure 4: Methods of inducing muscle atrophy in cell models

Caption

This figure highlights methods for inducing muscle atrophy in cell models, including primary cell cultures (A), nutrient deprivation (B), drug induction (C), regulation by metabolic and inflammatory factors (D), Co-culture with cancer cells or exosomes (E), differentiation of iPSC into engineered muscles (F). These methods simulate different aspects of muscle atrophy, aiding in understanding and developing treatments for sarcopenia and cachexia.

iPSC: induced pluripotent stem cells. TNF-α: tumor necrosis factor-alpha.

Credit

Chenying Fu

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