Nuclei of ccRCC cells and nuclear speckles (IMAGE)
Caption
The nuclei of ccRCC cells taken from patient tumors. Inside these nuclei are nuclear speckles, seen in red. The nuclei on the left have a centralized, normal-like speckle pattern associated with better patient outcomes. Those on the right have a more dispersed, aberrant speckle pattern associated with lower survival rates.
Credit
Alexander lab/Cold Spring Harbor Laboratory
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