Formation of new nerve connections after acute spinal cord injury (IMAGE)
Caption
Top: An acute spinal cord injury leads to an interruption of motor nerve pathways, resulting in paraplegia, a paralysis of arm and leg muscles.
Center: The injured nerve pathways cannot recover sufficiently because inhibitors (Nogo) block the growth of new connections.
Bottom: With the treatment of antibodies that neutralize the inhibitors, new nerve connections can form and grow along preserved tissue bridges. They lead to improved motor recovery.
Credit
Balgrist University Hospital
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