Clusters of tumor cells in the 3MIC (IMAGE)
Caption
Clusters of about a hundred tumor cells labelled with red fluorescence were grown inside a transparent jelly-like structure and surrounded by immune cells called macrophages—labelled in green. Tumor cells on the left are growing under normal culture conditions. Tumor cells on the right were grown in a nutrient- and oxygen-scarce region within the 3MIC. These different environments produced dramatic changes in the metastatic features on these tumor cells: almost no migration in cells from the tumor cluster on the left, while the cluster on the right—grown under poor conditions —produced lots of finger-like streams of migratory cells.
Credit
Carmofon Lab/NYU
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License
CC BY