the LoCoHD curves (top graphs) and structures (bottom panels) of His276 and Met197 in podocin (IMAGE)

Eötvös Loránd University

the LoCoHD curves (top graphs) and structures (bottom panels) of His276 and Met197 in podocin

Caption

The figure shows the LoCoHD curves (top graphs) and structures (bottom panels) of His276 and Met197 in podocin, two strongly bimodal amino acids, measured from a molecular dynamics simulation. In the simulation, amino acid His276 plays a role in shortening a helix, while amino acid Met197 is responsible for filling a hydrophobic cavity.

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Image: Eötvös Loránd University

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