Why women need to be prioritized in longevity research
Peer-Reviewed Publication
Updates every hour. Last Updated: 26-Oct-2026 09:16 ET (26-Oct-2026 13:16 GMT/UTC)
Why do women, on average, live longer than men, yet often face a greater burden of chronic disease later in life? Why do some of the most fertile animals in nature, including queen bees and naked mole-rat queens, also live exceptionally long lives? A perspective, to be published on August 6th in Cell, introduces the Reproductive Resilience Hypothesis (RRH), a new way to think about these questions. The hypothesis, developed by Buck Institute researchers proposes that reproduction and longevity, often seen as opposing biological forces, may be tightly linked in the context of life history. The authors posit that women could be the key players in efforts to discover ways to extend human healthspan.
People with type 2 diabetes and obesity may benefit from treatment with tirzepatide. Tirzepatide, marketed under the brand name Mounjaro, can reduce the risk of heart attacks and hospitalizations due to infections by about one-third each compared with a conventional diabetes medication. Researchers at the Technical University of Munich (TUM) and Harvard Medical School demonstrated this using health insurance data.