Women live longer than men in nearly every country in the world, yet they experience higher rates of disability, dementia and many other age-related conditions. Scientists have long noted these differences, but they still do not fully understand why they occur — or how that knowledge can be used to improve healthy aging. A new $7.5 million, five-year grant from the National Institutes of Health will establish the USC Geroscience Specialized Center of Research Excellence on Sex Differences in Aging (GeroSCORE) to address that challenge.

Biologists show how the prefrontal cortex, a brain region associated with learning more flexible behaviors, can sometimes block the ability of a mouse to adopt a better way to solve a problem.

The tissue microenvironments surrounding HIV-infected immune cells look a lot like those surrounding cancerous tumors, reports a new Northwestern University study. 

The findings help explain why HIV has been so difficult to cure. Scientists found that viral reservoirs exist within tissue microenvironments that resemble immune-suppressive tumor microenvironments, suggesting that future HIV cure strategies may benefit from approaches traditionally used in cancer therapy.