A diet that severely limits carbohydrates but is high in fat has the greatest health benefits for people with obesity compared to a Mediterranean diet or a low-fat diet, according to a clinical trial publishing August 27 in the Cell Press journal Cell Metabolism. After following a ketogenic (or “Keto”) diet for four to five months, about 50% of a group of participants with obesity and prediabetes no longer met the criteria for prediabetes. 

AMHERST, Mass. — Having established the effectiveness of her nanoparticle drug-delivery system for cancer immunotherapy, University of Massachusetts Amherst researcher Prabhani Atukorale, has been awarded $2.5 million from the National Institutes of Health to broaden the scope of her vaccine research to include treating those with active cancer.

In a new study, researchers describe the development and validation of a multi-ancestry polygenic risk score (PRS) for AD that performs much better than previously constructed ones, especially for genetically diverse groups. This expanded representation of population groups is crucial for developing more robust and universally applicable PRS models, which can improve risk prediction among an ancestrally diverse group of patients.