About 75% of older adults in the ICU develop delirium, a state of confusion with serious short and long-term health consequences including an increased risk of post-ICU dementia. A multi-center randomized controlled trial of critically ill adults aged 50 and older admitted to ICUs suggests the need for further study of music therapy in critically ill older adults. Results of the The Decreasing Delirium through Music in Critically Ill Older Adults Trial are reported in JAMA Internal Medicine.

Scientists have identified an unusual type of brain cell that may play a vital role in progressive multiple sclerosis (MS), likely contributing to the persistent inflammation characteristic of the disease. The discovery, reported today in Neuron, is a significant step towards understanding the complex mechanisms that drive the disease and provides a promising new avenue for research into more effective therapies for this debilitating condition.