Wayne State researchers lead $5.7 million NIH study tackling insulin resistance and type 2 diabetes
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Updates every hour. Last Updated: 21-Oct-2026 18:16 ET (21-Oct-2026 22:16 GMT/UTC)
A new study showed a greater prevalence of poor kidney health among young girls and women in Nicaragua than previously known, as this population is often excluded from CKDu research because they are rarely diagnosed with CKDu. Their elevated risk was also strongly associated with high body mass index levels, indicating elevated risk of metabolic kidney disease. While the researchers did identify poor kidney health among heat-exposed young males working in sugarcane fields, the majority of participants who exhibited higher poor kidney health did not work in heat-intensive environments. Both of these findings were unexpected.
New research from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) has identified a promising new therapeutic target and developed an experimental compound that reduces fat buildup, inflammation, liver injury and scarring in preclinical models, laying the groundwork for a potential new treatment.
This NIH-funded research builds directly on the discovery of Bachmann-Bupp syndrome (BABS), an ultra-rare genetic disorder caused by mutations in the ODC1 gene that disrupt the body’s polyamine pathway. The funding will advance research into polyaminopathies, a group of rare genetic disorders that can cause neurodevelopmental challenges, and support clinical studies, molecular diagnosis and treatment development.