Scientists identify agent of transformation in protein blobs that morph from liquid to solid
Peer-Reviewed Publication
Updates every hour. Last Updated: 12-May-2025 16:09 ET (12-May-2025 20:09 GMT/UTC)
An international research collaboration led by Rutgers University-New Brunswick scientists that examined microscopic blobs of protein found in human cells has discovered that some morph from an almost honey-like substance to a hard candy-like solid.
These mysterious droplets, known as biomolecular condensates, solidify when they carry a high proportion of the protein alpha-synuclein, the scientists reported in Science Advances. Clumps of alpha-synuclein are commonly found in the brain cells of people with Parkinson’s disease, a neurodegenerative brain disorder.
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