In a study of more than 5,000 mothers and their children, exposure to air pollution during the three months before pregnancy predicted higher child body mass index (BMI) and related obesity risk factors up to two years of age. In one of the largest studies to date of preconception environmental exposures, researchers from the Keck School of Medicine of USC, Duke University and Fudan University in Shanghai, China studied 5,834 mother-child pairs recruited from maternity clinics in Shanghai. They found that greater exposure to PM_2.5, PM₁₀ and NO₂ before pregnancy was linked to increases in BMI or BMIZ, a standardized score that shows how a child’s BMI compares to others of the same age and sex. The findings imply that the three months before conception are important, and that people who plan to bear children should consider taking measures to lower their air pollution exposure to reduce their children’s risk for obesity.

Doctors in the U.S. have reported feeling unprepared to care for people with disabilities and have revealed significant negative bias about this population, according to previous research. A new Northwestern Medicine study has found much of this could be rooted in their medical school training. 

Red meat consumption is an established risk factor for chronic conditions, including cardiovascular disease and type 2 diabetes. A new study by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard found that eating greater quantities of red meat, especially in processed forms, increased risk for dementia, too. Results, published online on January 15, 2025, in Neurology®, the medical journal of the American Academy of Neurology, highlight that replacing processed red meat with protein sources like nuts and legumes or fish may decrease dementia risk by approximately 20 percent.

Most treatments being pursued today to protect against Alzheimer’s disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research from Mass General Brigham and Washington University School of Medicine in St. Louis points to a novel—and noble—approach: using Xenon gas. The study found that Xenon gas inhalation suppressed neuroinflammation, reduced brain atrophy, and increased protective neuronal states in mouse models of Alzheimer’s disease. Results are published in Science Translational Medicine, and a phase 1 clinical trial of the treatment in healthy volunteers will begin in early 2025.