22-Jul-2025
Misfolded proteins accumulate in the mitochondria of patients with type 2 diabetes
Michigan Medicine - University of MichiganPeer-Reviewed Publication
In a study published in Nature Metabolism, researchers at the University of Michigan found that mitochondria also accumulate misfolded proteins, which kills β-cells.
- Journal
- Nature Metabolism
- Funder
- Breakthrough T1D, NIH/National Institutes of Health, Department of Veterans' Affairs, American Diabetes Association, ADA Pathway to Stop Diabetes Accelerator Award, Wellcome Trust Investigator Award, UKRI MRC Programme grant, Diabetes UK, NIH-NIDDK project grant, CIHR-JDRF Team grant, Innovation Canada John R. Evans Leader Award, Swiss National Science Foundation