First-in-human clinical trial shows promising results for new Lassa fever vaccine
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Updates every hour. Last Updated: 27-Oct-2026 00:16 ET (27-Oct-2026 04:16 GMT/UTC)
Researchers at the University of Maryland School of Medicine’s Center for Vaccine Development and Global Health (CVD) reported encouraging results from an early clinical trial that tested a new dual vaccine against Lassa fever and rabies. The study, published today in the journal Nature Medicine, found that the vaccine was safe and induced immune responses against both viruses. There are currently no vaccines against Lassa fever on the market.
Researchers commonly test drugs in simplified lab conditions, often at room temperature. Northwestern scientists discovered drugs behave differently at body temperature and with physiologically relevant calcium levels. Findings could improve drug screening and lead to therapies that work only in diseased cells.
In a new study, Northwestern University scientists developed a 90s-style video game to help chronic stroke survivors regain lost arm function. While wearing a small device on their impaired arm and using a laptop computer, players use their arm muscles to complete tasks such as flying a helicopter around the screen to hit a moving target. The muscle retraining helps separate the brain’s uncoordinated movement signals, enabling muscles to work independently again.
After six weeks of the game-based therapy, chronic stroke survivors improved arm function by as much as 7.8 times as much as those in the control group.Kyoto, Japan -- Dementia makes most things in life more difficult, including hospital care. Though often essential for patients suffering from severe acute illness, hospital care can be confusing for persons with dementia, or PWD. Compared to older adults without dementia, PWD in the United States visit the emergency room and are hospitalized at higher rates. In these cases, the decision for a hospital stay requires a delicate balance between the potential benefits and risks of hospital care.
Previous research has suggested that PWD who are admitted to the hospital have higher mortality rates and spend more days away from home in the following months than their non-admitted counterparts. However, a possible explanation for this is that the admitted patients are already in worse condition -- in unmeasured ways -- than their counterparts.
Intrigued by this conundrum, a team of researchers at Kyoto University and the University of California, Los Angeles examined whether hospital admissions have a causal effect on health outcomes for persons with dementia, and also investigated the effect on their subsequent healthcare spending.