Colorectal cancer is the second leading cause of cancer-related death globally.

Although some of the molecular changes associated with colorectal cancer are known, how they contribute to cancer development is not yet well defined.

In a study published in Journal of Clinical Investigation, researchers used mouse models and studies of colorectal cancer tissues to show that loss of SOX9 gene promotes tumor progression and the pathway it regulates can be a potential target for future treatments.

If you want to do your best, most creative work, moving to a new place – or working from several places – can accelerate the process, according to a new study of Nobel Prize winners. Researchers found that Nobel laureates who moved more frequently began their prize-winning work up to 2 years earlier than did laureates who never moved. Those who worked in multiple locations started their innovative work up to 2.6 years earlier.

Providing hearing aids and advice on their use may preserve social connections that often wane as we age, a new study shows. Its authors say that this approach could help ease the loneliness epidemic that older Americans face.

New research results from mouse and swine studies, describe a vaccine that protects against H1N1 swine flu and can also protect against human and bird influenza variants.  Post-experiment regression analysis indicate immunity would not dissipate for 10 years. The latest study confirms previous results against the H3 influenza A subtype with the more genetically diverse and frequently circulating H1 subtype.