The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer’s disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady. The research, published in the August29, 2025 issue of Cell Reports, also shows that feeding the mice a high fiber diet reduces AD-related frailty, including tremor.

Metals, particularly nickel and vanadium, and sulfate particles are the components of fine particulate air pollution (PM2.5) that most strongly contribute to the association between long-term exposure to air pollution and hospitalization among asthma sufferers, according to a new study led by Harvard T.H. Chan School of Public Health.

A new U-M study uncovers how fentanyl and a popular additive, the animal tranquilizer xylazine, interact in a mouse model.  

Cardiologists have long known that up to half of all heart attacks and strokes occur among apparently healthy individuals who do not smoke and do not have high blood pressure, high cholesterol, or diabetes, the “standard modifiable risk factors” which doctors often call “SMuRFs.”  How to identify risk among the “SMuRF-Less” has been an elusive goal in preventive cardiology, particularly in women who are often under-diagnosed and under-treated.