Specific way genetic material is organized in cells determines its ability to adapt to resist treatment. Scientists modulated this organization with an FDA-approved drug on the market. Strategy prevented cancer cells from adapting, making chemotherapy more effective in lab cultures and animal models of human cancer.

Researchers from Tufts University School of Dental Medicine have developed lab-grown skin that replicates the complexity of scleroderma. Made from patient-derived cells, the 3D tissue model increases understanding of how this and fibrotic diseases progress.