One dose of antibiotic treats early syphilis as well as three doses
Peer-Reviewed Publication
Updates every hour. Last Updated: 10-Sep-2025 05:11 ET (10-Sep-2025 09:11 GMT/UTC)
Researchers funded by the National Institutes of Health (NIH) have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians in the United States and elsewhere. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit. The results were published today in The New England Journal of Medicine.
Scientists from Auburn University and international collaborators have uncovered the strongest protein-protein bond ever recorded in nature. Their discovery explains why Staphylococcus aureus, a leading cause of skin infections, clings so stubbornly to human skin — and points to new ways of fighting antibiotic-resistant bacteria.
Research offers new approach to targeting the pervasive disorder