Spatial analysis finds immune-rich pockets in diffuse large B-cell lymphoma tumors with clear treatment potential
Peer-Reviewed Publication
Updates every hour. Last Updated: 15-Dec-2025 14:11 ET (15-Dec-2025 19:11 GMT/UTC)
By analyzing the tumor environment of diffuse large B-cell lymphoma (DLBCL), researchers from The University of Texas MD Anderson Cancer Center identified seven distinct cellular microenvironments, providing a framework to develop therapies that will engage a patient’s immune system to attack cancer cells. Each microenvironment showed a different mix of cells and its own pattern of communication between tumor B-cells and immune cells.