Moffitt study finds new immunotherapy strategy for enhancing melanoma treatment
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Updates every hour. Last Updated: 4-May-2025 23:09 ET (5-May-2025 03:09 GMT/UTC)
Research team from Wesley Center for Immunotherapy at UH Seidman Cancer Center Awarded Top Scoring Abstract Award at the 2025 International Society for Cell and Gene Therapy Annual Meeting
David Wald, MD, PhD and colleagues abstract was selected based on their work to develop a less than one day CAR T-cell Therapy Manufacturing Process
A research team led by Prof. Liangliang Dai of Northwestern Polytechnical University (NWPU) has launched a platelets-based drug delivery system. The study was published in Science Bulletin.
Metastasis and heterogeneity pose major challenges in cancer treatment. Although chemoimmunotherapy shows promising efficacy, its therapeutic impact is limited by off-target effects and differences in the delivery sites of chemotherapeutic drugs and immunosuppressants. To overcome the limitation, the research team proposed an engineered platelets (Pts)-based nano-aircraft, Pts@DOX/HANGs@Gal, was constructed with an internally loaded chemotherapeutic drug, doxorubicin, and externally grafted reduction-responsive hyaluronidase-cross-linked nanospheroids loaded with the immunosuppressant galunisertib for precise tumor chemo-immunotherapy.
A study led by the Hospital del Mar Research Institute has established the importance of immunoglobulin A, an antibody that is part of the immune system, in generating a response to pneumonia vaccines.
Researchers have found that the absence of this antibody leads to an overgrowth of gut microbiota, triggering an excessive and sustained immune system response, which ultimately becomes exhausted and fails to respond effectively to vaccines.
The study, published in Science Advances, opens the door to exploring the possibility of early immunoglobulin therapy administration to prevent this process and reduce the risk of potentially dangerous infections, even in at-risk individuals without a diagnosed immunodeficiency
Professor JianQiao Zhou’s team at Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, has developed a latent diffusion model named CoLDiT. This model generates high-quality breast ultrasound images across different BI-RADS categories to overcome medical data sharing barriers. The study, titled “Synthetic Breast Ultrasound Images: A Study to Overcome Medical Data Sharing Barriers,” was published in the journal Research (DOI: 10.34133/research.0532).
New research from Edith Cowan University (ECU) has confirmed that erectile dysfunction in patients living with prostate cancer could be significantly improved through regular exercise.
A new type of antibody which stimulates the immune system to target cancer cells slows tumour growth, according to new research.
Researchers at Washington University in St. Louis are discovering the electrochemical properties of biomolecular condensates which could help in development of cancer or ALS treatments