EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 15-Dec-2025 19:11 ET (16-Dec-2025 00:11 GMT/UTC)

First truly global picture of wide inequalities in care for women’s cancers

London School of Hygiene & Tropical Medicine
Peer-Reviewed Publication

One in five women with breast or cervical cancer in low- and middle-income countries (LMICs) are diagnosed at an early stage, compared with more than one in three in high-income countries (HICs), new research suggests. For ovarian cancer, the proportion of women diagnosed with early-stage disease was generally lower than 20% (one in five) worldwide, although the situation remains slightly worse for women in LMICs.

Journal: The Lancet
Funder: European Research Council

University of Louisville, UofL Health receive $11.5 million to develop new cancer immunotherapies

University of Louisville
Grant and Award Announcement

UofL has received $11.5 million in new funding from the NIH to support continuing research to develop therapies that activate the immune system against cancer and to train the next generation of cancer researchers and oncologists.

Funder: NIH/National Institute of General Medical Sciences

Moffitt study shows gene expression test can help identify melanoma patients at low risk of lymph node spread

H. Lee Moffitt Cancer Center & Research Institute
Peer-Reviewed Publication

A large multicenter clinical trial published in JAMA Surgery shows that a gene expression profile–based test can reliably identify melanoma patients who have a low risk of cancer spreading to their lymph nodes. The findings could help guide decisions about whether to perform sentinel lymph node biopsy, a standard but invasive staging procedure.

Journal: JAMA Surgery
Funder: SkylineDx

ESMO 2025: MSK presents new research, including latest on lung and pancreatic cancer treatments

Memorial Sloan Kettering Cancer Center
Reports and Proceedings

MSK highlights from the recent European Society for Medical Oncology (ESMO) Congress include promising findings on new lung, pancreatic, and colorectal cancer treatments and new insights for how molecular testing can guide personalized medicine.

Meeting: ESMO 25

Adding chemotherapy to radiation causes greater short-term decline in quality of life for patients with cervical cancer

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

The findings highlight the importance of providing extra supportive care during the most challenging phase of treatment—weeks three to seven—when declines in quality of life are most pronounced.

Journal: Gynecologic Oncology
Funder: NIH/National Cancer Institute, NRG Oncology

UCLA scientists develop one-product-fits-all immunotherapy for breast cancer

University of California - Los Angeles
Peer-Reviewed Publication

UCLA researchers have developed a CAR-NKT cell therapy that has shown to be more effective than current immunotherapies at fighting cancer in tumor samples from late-stage triple-negative breast cancer patients.

While personalized treatments can cost six figures and require weeks to manufacture, this therapy can be mass-produced from donated blood stem cells and stored ready-to-use at about $5,000 per dose.

The same cell product could potentially be used to treat multiple solid tumors like ovarian, pancreatic and lung cancers — all of which express the protein mesothelin.

Journal: Journal of Hematology & Oncology

New genomic test could spare some people with melanoma from lymph node biopsy surgery

Mayo Clinic
Peer-Reviewed Publication

A genomic test co-developed by Mayo Clinic and SkylineDx can identify whether people with melanoma are at low or high risk for cancer in their lymph nodes — a finding that could guide treatment decisions and help many people avoid lymph node biopsy surgery. The study results are published in JAMA Surgery.

Journal: JAMA Surgery

New technique allows researchers to track chemotherapy drugs inside of cells

University of Illinois Urbana-Champaign Cancer Center at Illinois
Peer-Reviewed Publication

Scientists have made incredible progress in developing cancer therapies that help patients across cancer types. However, they face limitations in determining the results of drug effectiveness, as well as ensuring even distribution among all cancers cells because of the highly compact nature of tumors. Researchers are working to change that by giving chemotherapy drugs a kind of chemical ‘signal’ that allows them to be tracking inside of cells.

Journal: Analytical Chemistry

Researchers develop a less invasive, more effective method to analyze immunotherapy efficacy

University of Illinois Urbana-Champaign Cancer Center at Illinois
Peer-Reviewed Publication

Immunotherapy has been one of the most promising advancements in cancer treatment, however, consistency in immunotherapy treatment effectiveness remains a formidable challenge. Now, researchers are aiming to take the guesswork out of cancer treatments through a predictive model for determining immunotherapy treatment effectiveness.

Journal: Nature Communications

Spatial analysis finds immune-rich pockets in diffuse large B-cell lymphoma tumors with clear treatment potential

University of Texas M. D. Anderson Cancer Center
Peer-Reviewed Publication

By analyzing the tumor environment of diffuse large B-cell lymphoma (DLBCL), researchers from The University of Texas MD Anderson Cancer Center identified seven distinct cellular microenvironments, providing a framework to develop therapies that will engage a patient’s immune system to attack cancer cells. Each microenvironment showed a different mix of cells and its own pattern of communication between tumor B-cells and immune cells.

Journal: Nature Genetics

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