NUS team launches open-access tool to decode DNA change patterns in breast cancer
Peer-Reviewed Publication
Updates every hour. Last Updated: 22-Jun-2026 13:15 ET (22-Jun-2026 17:15 GMT/UTC)
A study led by Dr Jason Pitt, Principal Investigator at the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, has identified eight new "signatures" of DNA patterns (gains and/or losses) in breast cancer. By analysing nearly 2,800 genomes, the team systematically profiled changes in the number of DNA copies in breast cancer, with the goal of better understanding the underlying mechanisms of tumour development and evaluating how these structural genomic changes relate to clinical outcomes.
The identified signatures could help refine future diagnostic tools, as well as to better match breast cancer patients with targeted therapies.
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