Targeted alpha therapy: a breakthrough in treating refractory skin cancer
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Updates every hour. Last Updated: 7-Sep-2025 05:11 ET (7-Sep-2025 09:11 GMT/UTC)
A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically summarized the interactions between aging, biological rhythms, and cancer. Their work reveals the underlying mechanisms and clinical applications in tumor biology. The findings were published in the journal of Research entitled "The Common Hallmarks and Interconnected Pathways of Aging, Circadian Rhythms, and Cancer: Implications for Therapeutic Strategies" (Research, 2025, DOI: 10.34133/research.0612).
We’re all familiar with the outward signs of aging, such as sagging skin or thinning hair. But many age-related changes start within our cells, even our DNA, which can wear and tear over time. One creature has a way to reverse this process, at least temporarily. A hamster-sized primate from Madagascar, the fat-tailed dwarf lemur can turn back the aging clock during its annual hibernation season, according to markers of cellular aging called telomeres.