27-Jan-2025
Cancer risk established before birth
Van Andel Research InstitutePeer-Reviewed Publication
A person’s lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study by Van Andel Institute scientists. The findings, published in Nature Cancer, identified two distinct epigenetic states that arise during development and are linked to cancer risk. One of these states is associated with a lower lifetime risk while the other is associated with a higher lifetime risk.
- Journal
- Nature Cancer
- Funder
- Max-Planck-Gesellschaft, European Research Council, Van Andel Research Institute, Van Andel Institute Metabolism & Nutrition (MeNu) Program, NIH/National Human Genome Research Institute, NIH/National Institute of Diabetes and Digestive and Kidney Diseases, NIH/National Institute of Allergy and Infectious Diseases, Chan Zuckerberg Initiative, Human Frontier Science Program Long-Term Fellowship