EurekAlert! Cancer Research - News Releases

News Releases

Updates every hour. Last Updated: 26-Apr-2025 21:08 ET (27-Apr-2025 01:08 GMT/UTC)

How hypoxia helps cancer spread

Johns Hopkins Medicine
Peer-Reviewed Publication

Scientists at the Johns Hopkins Kimmel Cancer Center have identified 16 genes that breast cancer cells use to survive in the bloodstream after they’ve escaped the low-oxygen regions of a tumor. Each is a potential therapeutic target to stop cancer recurrence, and one – MUC1 – is already in clinical trials.

Journal: Nature Communications
Funder: Jayne Koskinas Ted Giovanis Foundation for Health and Policy, NCI/ SKCCC Core grant, National Cancer Center

Global disparities of cancer and its projected burden in 2050

JAMA Network
Peer-Reviewed Publication

About The Study: In this cross-sectional study based on data from 2022, cancer disparities were evident across Human Development Index, geographic regions, age, and sex, with further widening projected by 2050. These findings suggest that strengthening access to and quality of health care, including universal health insurance coverage, is key to providing evidence-based cancer prevention, diagnostics, and care.

Journal: JAMA Network Open

New study reveals racial disparities in breast cancer diagnosis and outcomes in Canada

University of Ottawa
Peer-Reviewed Publication

Canada’s current national screening guidelines for breast cancer are less appropriate for women of certain race and ethnicity groups since they are diagnosed at younger ages with more advanced stages of the disease. The new findings from a University of Ottawa research team underscore the urgent need to reevaluate screening guidelines to account for racial and ethnic differences and ensure equitable healthcare access, including earlier screening, to improve outcomes for all women.

Journal: The Oncologist
Funder: Women and Gender Equality Canada, Public Health Agency of Canada

Foam cells in brain tumours

Lund University
Peer-Reviewed Publication

A research team at Lund University in Sweden has discovered a certain type of cells – foam cells – in patients with the aggressive brain tumour glioblastoma. It has been shown how these cells accelerate the cancer’s growth and that this can be successfully inhibited using a drug developed for arteriosclerosis.

Journal: Science Translational Medicine
Funder: The Swedish Research Council, Swedish Cancer Society, Swedish Childhood Cancer Fund, ALF, Mrs. Berta Kamprad Foundation, Sjöberg Foundation, and a donation from Viveca Jeppsson.

New molecular classification of gastrointestinal stromal tumors guides precision treatment

BGI Genomics
Peer-Reviewed Publication

BGI Genomics and partners have published a transformative study in Nature Communications that links genetic differences in GISTs to tailored treatment strategies. The discovery of YLPM1 as a tumor suppressor gene marks a significant step in precision oncology.

Journal: Nature Communications

Druggability, molecular targets, and nanocarrier delivery of natural triterpenoid celastrol against chronic diseases

Compuscript Ltd
Peer-Reviewed Publication

https://www.scienceopen.com/hosted-document?doi=10.15212/AMM-2024-0044

Announcing a new publication for Acta Materia Medica journal. Celastrol is an active compound from the root of Tripterygium wilfordii Hook F that shows great potential in the treatment of inflammation, cancer, neurodegeneration, diabetes, and obesity. However, the clinical application of celastrol has been hindered by its low bioavailability and severe systemic toxicity.

Journal: Acta Materia Medica

An old drug with new tricks

Medical University of South Carolina
Peer-Reviewed Publication

Despite the promise against cancer shown by the anti-malarial drug hydroxychloroquine, clinical trials have proved disappointing, partly because cancer cells develop resistance to the drug. MUSC Hollings Cancer Center researchers report in Cell Cycle that resistance to hydroxychloroquine occurs not by restoring cellular recycling, as had been expected, but by affecting the division, metabolism and export of cancer cells. These findings could inform new combination therapies with hydroxychloroquine, enhancing the drug’s effectiveness against cancer.

Journal: Cell Cycle
Funder: NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health, NIH/National Institutes of Health

Researchers awarded $2.5 million grant to increase lung cancer screenings in underserved communities

University of California - Los Angeles Health Sciences
Grant and Award Announcement

The funding will support a new initiative aimed at reducing disparities in lung cancer screening across Los Angeles County.

Funder: Bristol-Myers Squibb Foundation

Researchers home in on tumor vulnerabilities to improve odds of treating glioblastoma

University of Toronto
Peer-Reviewed Publication

A team led by researchers at the University of Toronto has uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. These targets were identified through a screen for genetic vulnerabilities in patient-derived cancer stem cells that represent the variability found in tumours.

Journal: Cancer Research

Awareness of lung cancer screening remains low

Medical University of South Carolina
Peer-Reviewed Publication

A majority of people who are eligible for lung cancer screening responded that they hadn't heard of the test or hadn't discussed it with a clinician.

Journal: JAMA Network Open
Funder: NIH/National Institutes of Health, MUSC Hollings Cancer Center