Does the motion of our DNA influence its activity?
Peer-Reviewed Publication
Updates every hour. Last Updated: 24-Jun-2026 08:15 ET (24-Jun-2026 12:15 GMT/UTC)
Salk Institute scientists find the genome’s dynamic 3D shape influences gene expression, and that the protein NIPBL is a key facilitator of genome structures that inform cell identity. Their findings may inform new therapeutics for disorders related to dysfunctional genome folding, including some cancers and developmental disorders such as autism-related disorders.
A minimally invasive targeted treatment called salvage focal therapy, which targets just the cancerous area of the prostate, can treat men whose prostate cancer has recurred after radiotherapy with much fewer side effects and less impact on their quality of life, according to a new study.
The intricate, lifelong conversation between blood vessels and immune system is fundamental to health, and its breakdown is pathogenic to many diseases. A review, published on February 10, 2026, in Immunity & Inflammation by Prof. Yihai Cao at the Karolinska Institute, Sweden, provides a systematic and mechanistic framework for understanding this dynamic crosstalk, offering a unified perspective on how vascular endothelial cells orchestrate immune responses and how their dysfunction leads to pathology.
Adult survivors of childhood cancers are at higher risk for another cancer – such as breast, colorectal, sarcomas and thyroid cancer – that is not a relapse of their original illness. Previous cancer therapies are largely responsible, however up to 13 percent of survivors also have hereditary predisposition that elevates their risk of subsequent cancer. A recent clinical trial found that genetic services via remote centralized telehealth and in collaboration with primary care increased the uptake of genetic counseling and testing in this population. Results were published in Lancet Regional Health – Americas.
The February tip sheet from Sylvester Comprehensive Cancer Center features a range of timely cancer-related story ideas that may be of interest. Highlights include new strategies to overcome chemotherapy resistance, efforts to build resilience among lymphoma patients, multidisciplinary teams exploring the sea and sky for novel cancer cures and insights, and more.
A team of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER) and the University of Seville, in collaboration with the Virgen Macarena University Hospital, have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks. This study, which focused on the circadian protein Cryptochrome1 (CRY1), suggests that the time of day when radiotherapy is administered can significantly influence the effectiveness of treatment for certain types of cancer.
Listeria bacteria generate a unique innate immune response that is being harnessed to boost the immune system in cancer patients. Scientists at UC Berkeley and a spinoff company eliminated the bacteria’s ability to cause disease while retaining its ability to rev up production of gamma delta T cells, which are associated with increased survival in cancer patients. They demonstrated the therapy’s safety in mice and seek approval to test it in pediatric leukemia patients.