The continuous movement of the vocal cords weakens and eventually stops as laryngeal cancer progresses. Researchers have, for the first time, discovered that restoring cellular vibration reduces the aggressiveness of advanced vocal cord cancer. When cancer cells were exposed to sound-wave vibration, a protein that promotes cancer growth and severity decreased.

With up to $25 million from Cancer Grand Challenges, an international team led by UC San Diego professor Ludmil Alexandrov, will unlock the secrets of DNA's "fingerprints."

Cancer cell-derived small extracellular vesicles (sEVs) can travel from distant tumors through the bloodstream and kidneys and be excreted into urine, as reported by researchers at Science Tokyo. Using sophisticated molecular tagging systems in mouse models of brain, lung, and pancreatic cancer, the researchers directly traced sEVs from tumors to urine. They also revealed that the kidney’s glomerular cells actively transport sEVs across the filtration barrier, supporting their use in emerging urine-based cancer diagnostics.

A multidisciplinary team wanted to find the best diet to slow tumor growth after a breast cancer diagnosis. Instead, they found one that accelerated it: a high-fat diet. The researchers engineered a tumor model using a human plasmalike medium to re-create a more realistic microenvironment around tumors, and this allowed them to replicate the biochemical effects of nutrients from food. They discovered a high-fat diet accelerates tumor growth and invasion and causes an increase in the enzyme MMP1, which is associated with a poor prognosis.