A landmark clinical guideline has been released to standardize the treatment of 26 common dermatological and aesthetic conditions, including melasma, nevus of Ota, and acne scars. Developed by the Chinese Medical Association and the Chinese Association of Plastics and Aesthetics, this guideline synthesizes high-level international evidence to provide standardized protocols for energy-based devices (lasers, IPL, radiofrequency). It aims to resolve the lack of systematic standards in the rapidly growing field of aesthetic medicine.

Metal oxides serve as the critical active components in oxide-zeolite (OXZEO) catalysis, a transformative technology that is redefining syngas conversion to light olefins by surpassing the limitations of traditional Fischer-Tropsch processes. A new review illuminates how these metal oxides selectively activate CO and H₂ to regulate product distribution, leveraging advanced in-situ and quasi-in-situ characterization techniques to unravel previously elusive active sites and reaction pathways. These mechanistic insights not only address longstanding challenges in catalyst design but also provide a roadmap for accelerating the industrial translation of OXZEO technology.

Acute kidney injury (AKI) remains a life-threatening condition with high morbidity and mortality, yet no specific treatment is currently available. A key driver of AKI is the depletion of nicotinamide adenine dinucleotide (NAD⁺) in renal cells, which disrupts energy metabolism and leads to ATP deficiency and oxidative stress. The enzyme QPRT, essential for NAD⁺ synthesis, is markedly reduced during AKI—making it a promising but previously unexplored therapeutic target.

Now, researchers have developed a bioengineered enzymatic nanovesicle that restores NAD⁺ levels through dual mechanisms: delivering QPRT to boost NAD⁺ synthesis, while releasing olaparib to curb NAD⁺ consumption. This comprehensive metabolic reprogramming repairs mitochondria, enhances energy production, and reduces oxidative stress. The approach proved effective across multiple AKI models, including high‑dose chemotherapy‑induced kidney dysfunction, highlighting its potential as a safe and powerful therapeutic strategy.